RESEARCH PORTFOLIO: PUBLICATIONS

Publications

2023

Collom C, Pradhan SH, Liu J, Sharma VK, and Sayes CM*. (2023). Toxicity of binary mixtures of copper, lead, and glyphosate on neuronal cells. Journal of Hazardous Materials Advances. (accepted, in press).

Pradhan SH, Gibb M, Kramer AT, and Sayes CM*. (2023). Peripheral (lung-to-brain) exposure to diesel particulate matter induces oxidative stress and increased markers for systemic inflammation. Environmental Research (accepted, in press).

Gibb M and Sayes CM*. (2023). An in vitro alveolar model allows for the rapid assessment of particles for respiratory sensitization potential. International Journal of Molecular Sciences (accepted, in press).

Sheikh A, Zechmann B, Sayes CM, Taube JH, & Greathouse KL (2023). A preparation of bacterial outer membrane with osmium tetroxide and uranyl acetate co-stain enables improved structural determination by transmission electron microscopy. Microscopy, dfad027.

https://doi.org/10.1093/jmicro/dfad027. PMID: 37148329

Ameh T, Zarzosa K, Dickinson J, Braswell WE, & Sayes CM. (2023). Nanoparticle surface stabilizing agents influence antibacterial action. Frontiers in Microbiology, 14.

doi: 10.3389/fmicb.2023.1119550. PMCID: PMC9947285. PMID: 36846763

Ameh T, Zarzosa K, Braswell WE, & Sayes CM*. (2023). Nanoparticle surface coatings produce distinct antibacterial effects that are consistent across diverse bacterial species. Frontiers in Toxicology, 5.

doi: 10.3389/ftox.2023.1119547. PMCID: PMC10022730. PMID: 36936540

Al Naggar Y, Sayes CM, Collom C, Ayorinde T, Qi S, El-Seedi HR, Paxton RJ, Wang K. (2023). Chronic exposure to polystyrene microplastic fragments has no effect 
on honey bee survival but reduces feeding rate and body weight. Toxics 11:100.

https://doi.org/10.3390/toxics11020100.

2022

Liu JY and Sayes CM*. (2022). Lung surfactant as a biophysical assay for inhalation toxicology. Current Research in Toxicology Dec 23:100101.

https://doi.org/10.1016/j.crtox.2022.100101. PMCID: PMC9849875. PMID: 36687216

Rothen-Rutishauser B, Gibb M, He R, Petri-Fink A, Sayes CM. (2022). Human lung cell models to study aerosol delivery – Considerations for model design and development. European Journal of Pharmaceutical Sciences Nov 21:106337.

https://doi.org/10.1016/j.ejps.2022.106337.  PMID: 36410570

Gibb M and Sayes CM. An in vitro alveolar model allows for the rapid assessment of chemical respiratory sensitization with modifiable biomarker endpoints. Chemico-Biological Interactions 2022 Dec 1;368:110232.

https://doi.org/10.1016/j.cbi.2022.110232.  PMID: 36309140

Baldovinos Y, Archer A, Salamanca J, Strongin RM, Sayes CM. Chemical Interactions and Cytotoxicity of Terpene and Diluent Vaping Ingredients. Chemical Research in Toxicology 2022 Oct 24.

https://doi.org/10.1021/acs.chemrestox.2c00218.  PMID: 36279315. PMCID: PMC10114068.

Liu JY, Pradhan SH, Hussain S, Sayes CM. Platform for Exposing Aerosolized Substances to Lung Surfactant and Alveolar Cells at the Air-Liquid Interface. ACS Chemical Health & Safety 2022 Sep 9;29(5):448-54.

https://doi.org/10.1021/acs.chas.2c00033

Ameh T, Gibb M, Stevens MD, Pradhan SH, Braswell WE, and Sayes CM. (2022). Silver and copper nanoparticles induce oxidative stress in bacteria and mammalian cells. Nanomaterials Jul 14;12(14):2402.                

https://doi.org/10.3390/nano12142402.  PMID: 35889626

Liu JY and Sayes CM. (2022). A Toxicological Profile of Silica Nanoparticles. Toxicology Research 11(4): 565–582.                        

https://doi.org/10.1093/toxres/tfac038.  PMID: 36051665.  PMCID: PMC9424711

Lujan H, Mulenos MR, Carrasco D, Zechmann B, Sayes CM. (2022) Engineered Aluminum Nanoparticle Induces Mitochondrial Deformation and is Predicated on Cell Phenotype. Nanotoxicology 24:1-8.

https://doi.org/10.1080/17435390.2021.2011974.  PMID: 35077653

Liu J, Gibb M, Pradhan SH, Sayes CM. (2022). Synergistic Cytotoxicity of Bromoacetic Acid and Three Emerging Bromophenolic Disinfection Byproducts against Human Intestinal and Neuronal Cells. Chemosphere 287(1):131794.

https://doi.org/10.1016/j.chemosphere.2021.131794.  PMID: 34438205

2021

Song S, Johnson KS, Lujan H, Pradhan SH, Sayes CM, Taube JH. (2021). Nanoliposomal delivery of microRNA-203 suppresses migration of triple-negative breast cancer through distinct target suppression. Non-coding RNA 7(3):45.

https://doi.org/10.3390/ncrna7030045.  PMID: 34449670.  PMCID: PMC8395754

Al Naggar Y, Brinkmann M, Sayes CM, Al-Kahtani SN, Dar S, El-Sedi HR, Giesy JP, Grünewald B. (2021). “Are Honey Bees at Risk from Microplastics?” Toxics 9:109.

https://doi.org/10.3390/toxics9050109

Patel I, Woodcock J, Beams R, Stranick SJ, Nieuwendaal R, Gilman JW, Mulenos MR, Sayes CM, Salari M, DeLoid G, Demokritou P, Harper B, Harper S, Ong KJ, Shatkin JA, Fox DM. Fluorescently Labeled Cellulose Nanofibers for Environmental Health and Safety Studies. Nanomaterials. 2021 Apr 15;11(4):1015.

10.3390/nano11041015. PMID: 33921179; PMCID: PMC8071547.

Gibb M, Pradhan SH, Mulenos MR, Lujan H, Liu J, Ede JD, Shatkin JA, Sayes CM. (2021). Characterization of a Human In Vitro Intestinal Model for the Hazard Assessment of Nanomaterials Used in Cancer Immunotherapy. Applied Sciences 11(5):2113.                                                                   

https://doi.org/10.3390/app11052113

Sayes CM and Singal M. (2021). The link between delivered aerosol dose and inflammatory responses: Exposing a lung Cell Co-Culture system to selected allergens and irritants. Journal of Aerosol Science 151:105677.

https://doi.org/10.1016/j.jaerosci.2020.105677

2020

Liu J, Mulenos MR, Hockaday WC, Sayes CM, Sharma VK. (2020). Ferrate(VI) pretreatment of water containing natural organic matter, bromide, and iodide: A potential strategy to control soluble lead release from PbO2(s). Chemosphere. 2021 Jan 263:128035.                                                                                                                          

doi: 10.1016/j.chemosphere.2020.128035. PMID: 33297053.

Liu J, Sayes CM, Sharma VK, Li Y, Zhang X. Addition of lemon before boiling chlorinated tap water: A strategy to control halogenated disinfection byproducts. Chemosphere. 2021 Jan 263:127954.                                                                                                  

doi: 10.1016/j.chemosphere.2020.127954. Epub 2020 Aug 13. PMID: 32854008; PMCID: PMC8134856.

Ede JD, Ong KJ, Mulenos MR, Pradhan S, Gibb M, Sayes CM, Shatkin JA. Physical, chemical, and toxicological characterization of sulfated cellulose nanocrystals for food-related applications using in vivo and in vitro strategies. Toxicology Research 2020 Dec 3;9(6):808-822.                                                                                                      

doi: 10.1093/toxres/tfaa082. PMID: 33447365; PMCID: PMC7786165.

Mulenos MR, Lujan H, Pitts LR, Sayes CM. Silver Nanoparticles Agglomerate Intracellularly Depending on the Stabilizing Agent: Implications for Nanomedicine Efficacy. Nanomaterials. 2020 Sep 30;10(10):1953.                                                            

doi: 10.3390/nano10101953. PMID: 33007984; PMCID: PMC7601179.

Liu J, Li Y, Jiang J, Zhang X, Sharma VK, Sayes CM. Effects of ascorbate and carbonate on the conversion and developmental toxicity of halogenated disinfection byproducts during boiling of tap water. Chemosphere. 2020 Sep;254:126890.             

doi: 10.1016/j.chemosphere.2020.126890. Epub 2020 Apr 24. PMID: 32957290; PMCID: PMC8056440.

Liu J, Olson C, Qiu N, Sayes CM. Differential Cytotoxicity of Haloaromatic Disinfection Byproducts and Lead Co-exposures against Human Intestinal and Neuronal Cells. Chemical Research in Toxicology 2020 Sep 21;33(9):2401-2407.                                     

doi: 10.1021/acs.chemrestox.0c00157. Epub 2020 Sep 2. PMID: 32803957.

Pradhan SH, Mulenos MR, Steele LR, Gibb M, Ede JD, Ong KJ, Shatkin JA, Sayes CM. Physical, chemical, and toxicological characterization of fibrillated forms of cellulose using an in vitro gastrointestinal digestion and co-culture model. Toxicology Research 2020 May 20;9(3):290-301.                                                                              

doi: 10.1093/toxres/tfaa026. PMID: 32670560; PMCID: PMC7329166.

Liu J, Lujan H, Dhungana B, Hockaday WC, Sayes CM, Cobb GP, and Sharma VK*. (2020). Ferrate(VI) pretreatment before disinfection: An effective approach to controlling unsaturated and aromatic halo-disinfection byproducts in chlorinated and chloraminated drinking waters. Environment International 1(138):105641.                                                    

https://doi.org/10.1016/j.envint.2020.105641

Lujan H, Romer E, Salisbury R, Hussain S, Sayes CM. Determining the Biological Mechanisms of Action for Environmental Exposures: Applying CRISPR/Cas9 to Toxicological Assessments. Toxicological Sciences 2020 May 1;175(1):5-18.                                  

doi: 10.1093/toxsci/kfaa028. PMID: 32105327.

Salazar-Medina AJ, Velazquez-Contreras EF, Sugich-Miranda R, Santacruz H, Navarro RE, Rocha-Alonzo F, Islas-Osuna MA, Chen PL, Christian SGB, Romoser AA, Dindot SV, Sayes CM, Sotelo-Mundo RR, Criscitiello MF. Immune response of human cultured cells towards macrocyclic Fe2PO and Fe2PC bioactive cyclophane complexes. PeerJ. 2020 Apr 20;8:e8956.                                                                            

doi: 10.7717/peerj.8956. PMID: 32341898; PMCID: PMC7179565.

Mulenos MR, Liu J, Lujan H, Guo B, Lichtfouse E, Sharma VK, Sayes CM*. (2020). Copper, silver, and titania nanoparticles do not release ions under anoxic conditions. Environmental Chemistry Letters 24:1-10.           

https://doi.org/10.1007/s10311-020-00985-z

Ong KJ, Ede JD, Pomeroy-Carter CA, Sayes CM, Mulenos MR, Shatkin JA*. A 90-day dietary study with fibrillated cellulose in Sprague-Dawley rats. Toxicology Reports 2020 Jan 20;7:174-182.                                                                                                                        

doi: 10.1016/j.toxrep.2020.01.003. PMID: 32021807; PMCID: PMC6994281.

2019

Mulenos MR, Zechmann B, Sayes CM. Sample preparation utilizing sputter coating increases contrast of cellulose nanocrystals in the transmission electron microscope. Microscopy. 2019 Dec 3;68(6):471-474.                                                                               

doi: 10.1093/jmicro/dfz032. PMID: 31696231.

Friedersdorf LE, Bjorkland R, Klaper RD, Sayes CM, Wiesner MR. Fifteen years of nanoEHS research advances science and fosters a vibrant community. Nature Nanotechnology. 2019 Nov;14(11):996-998.                                                                          

doi: 10.1038/s41565-019-0574-z. PMID: 31695147.

Ameh T and Sayes CM. The potential exposure and hazards of copper nanoparticles: A review. Environmental Toxicology and Pharmacology 2019 Oct;71:103220.                                            

doi: 10.1016/j.etap.2019.103220. Epub 2019 Jul 5. PMID: 31306862.

McMinn B, Duval AL, Sayes CM. An Adverse Outcome Pathway Linking Organohalogen Exposure to Mitochondrial Disease. Journal of Toxicology 2019 Apr 1;2019:9246495.                                                                                                                    

doi: 10.1155/2019/9246495. PMID: 31057609; PMCID: PMC6463576.

Lujan H, Criscitiello MF, Hering AS, Sayes CM. Refining In Vitro Toxicity Models: Comparing Baseline Characteristics of Lung Cell Types. Toxicological Sciences 2019 Apr 1;168(2):302-314.                                                                                                                     

doi: 10.1093/toxsci/kfz001. PMID: 30657991.

Sharma VK, Sayes CM, Guo B, Pillai S, Parsons JG, Wang C, Yan B, Ma X. Interactions between silver nanoparticles and other metal nanoparticles under environmentally relevant conditions: A review. Science of the Total Environment 2019 Feb 25;653:1042-1051.                                                                                                                                         

doi: 10.1016/j.scitotenv.2018.10.411. Epub 2018 Nov 3. PMID: 30759545.

Lujan H, Griffin WC, Taube JH, Sayes CM. Synthesis and characterization of nanometer-sized liposomes for encapsulation and microRNA transfer to breast cancer cells. International Journal of Nanomedicine 2019 Jul 11;14:5159-5173.                                             

doi: 10.2147/IJN.S203330. PMID: 31371954; PMCID: PMC6632672.

2018

Stewart M, Mulenos MR, Steele LR, Sayes CM. (2018). Differences Among Unique Nanoparticle Protein Corona Constructs:
A Case Study Using Data Analytics and Multi-Variant Visualization to Describe Physicochemical Characteristics. Applied Sciences 8:2669-2684.                                                    

https://doi.org/10.3390/app8122669

Sayes CM and Singal M. (2018). Optimizing a Test Bed System to Assess Human Respiratory Safety After Exposure to Chemical and Particle Aerosolization. Applied In Vitro Toxicology 4(2): 193.                                                                                           

DOI: 10.1089/aivt.2017.0043

2017

Lujan H and Sayes CM. Cytotoxicological pathways induced after nanoparticle exposure: studies of oxidative stress at the 'nano-bio' interface. Toxicology Research 2017 Jul 13;6(5):580-594.                                                                                                     

doi: 10.1039/c7tx00119c. PMID: 30090527; PMCID: PMC6062389.

Sharma VK, Yang X, Cizmas L, McDonald TJ, Luque R, Sayes CM, Yuan B, Dionysiou DD. (2017). Impact of metal ions, metal oxides, and nanoparticles on the formation of disinfection byproducts during chlorination. Chemical Engineering Journal 317:777-792.                                                              

https://doi.org/10.1016/j.cej.2017.02.071

Sayes CM and Lujan H. Characterizing the Nano-Bio Interface Using Microscopic Techniques: Imaging the Cell System is Just as Important as Imaging the Nanoparticle System. Current Protocols in Chemical Biology 2017 Sep 14;9(3):213-231.                      

doi: 10.1002/cpch.26. PMID: 28910854.

Benton EN and Sayes CM*. (2017). Environmental Factors Contribute to the Onset of Food Allergies. Journal of Environmental Science and Public Health 1(1):27-43.        

doi: 10.26502/JESPH.003

Sayes CM*, Aquino GV, Hickey AJ. Nanomaterial Drug Products: Manufacturing and Analytical Perspectives. AAPS Journal 2017 Jan;19(1):18-25.                                                 

doi: 10.1208/s12248-016-0008-x. Epub 2016 Nov 7. PMID: 27822601.

2016

Adegboyega NF, Sharma VK*, Cizmas L, and Sayes CM. (2016). “UV light induces Ag nanoparticle formation: roles of natural organic matter, iron, and oxygen”. Environmental Chemistry Letters 14.3 (2016): 353-357.         

https://doi.org/10.1007/s10311-016-0577-z

Clippinger AJ*, Ahluwalia A, Allen D, Bonner JC, Casey W, Castranova V, David RM, Halappanavar S, Hotchkiss JA, Jarabek AM, Maier M, Polk W, Rothen-Rutishauser B, Sayes CM, Sayre P, Sharma M, Stone V. Expert consensus on an in vitro approach to assess pulmonary fibrogenic potential of aerosolized nanomaterials. Archives of Toxicology 2016 Jul;90(7):1769-83.                                                                                  

doi: 10.1007/s00204-016-1717-8. Epub 2016 Apr 27. PMID: 27121469; PMCID: PMC4894935.

Song BK*, Nugent WH, Sayes CM, Bruce ED. Effects of Novel Oxygen Therapeutic on Systemic and Microcirculatory Variables in Sprague‐Dawley Rat Isovolemic Hemodilution Model. The FASEB Journal. 2016 Apr; 30:946-11.

https://doi.org/10.1096/fasebj.30.1_supplement.946.11

Gueldner J, Sayes C, Abel E, and Bruce E (2016) Emerging Associations of the ALDH2*2 Polymorphism with Disease Susceptibility. Journal of Drug Metabolism & Toxicology 7: 202.

doi: 10.4172/2157-7609.100020

Polk WW, Sharma M, Sayes CM, Hotchkiss JA, Clippinger AJ. Aerosol generation and characterization of multi-walled carbon nanotubes exposed to cells cultured at the air-liquid interface. Particle and Fibre Toxicology 2016 Apr 23;13:20.                                             

doi: 10.1186/s12989-016-0131-y. PMID: 27108236; PMCID: PMC4842292.

For a complete list of publications, including those published before 2016, see Google Scholar.